In contrast to protein oxidation rate (favourable vs. In 25 patients resting energy expenditure decreased 20 (18-27) % at 33☌ compared to 36☌ without differences between outcome groups (favourable vs. Measurements were correlated to outcome with repeated measures ANOVA, linear and logistic regression analysis. Indirect calorimetry was performed 5 times within 48 h after cardiac arrest. Patients after successful cardiopulmonary resuscitation undergoing targeted temperature management at 33☌ for 24 hours with subsequent rewarming to 36☌ and standardized sedation, analgesic and paralytic medication were included.

This prospective, observational cohort study was performed at the department of emergency medicine and a medical intensive care unit of a university hospital. Aim of this study was to correlate resting energy expenditure and substrate oxidation rates with targeted temperature management at 33☌ and outcome in patients after cardiac arrest.

Reduction of resting energy expenditure might be one mode of action. Targeted temperature management improves outcome after cardiopulmonary resuscitation.

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